Molcode has developed special QSAR ServiceTM for REACH legislation and provides fullydocumented REACH compliant Data based on experimental laboratory tests performed according to OECD Guidlines.
Molcode has introduced a three-step approach to proceed from request to REACH QSAR Reports:
Step 1 is free of charge for the customer, and provides information of the overall availability of QSAR endpoints for the particular substance based on an initial applicability domain (AD) evaluation. Sample report.
Step 2 (optional) provides substance based information with preliminary predictions for all available endpoints and/or scale/category estimations. It is intended to provide the customer with feedback of what the predictions will be like, and information to base their further strategy on. A fee of 100 EUR per substance applies. Sample report.
Step 3. Preparation of final substance and endpoint specific QSAR REACH compliant reports (QPRF). It includes fully documented prediction, category evaluation (where applicable), literature search and read-across. A FEE applies according to the price list for the selected endpoint. Sample QPRF.
For more information please contact Dr. Eneli Hark
List of available endpoints
| REACH | OECD | Endpoint | QSAR |
| Annex VII | |||
| 7.7 | 105 | Water Solubility | 1.3 |
| 7.8 | 107 | Partition Coefficient n-octanol/water | 1.6 |
| 8.3 | 429 | Skin Sensitisation | 4.6 |
| 8.3 | 406 | Skin Sensitisation | 4.6 |
| 8.4.1 | 471 | In vitro Gene Mutation study in Bacteria | 4.10 |
| 8.5.1 | 423 | Acute Toxicity - Oral | 4.2 |
| 9.1.1 | 202 | Acute toxicity for Daphnia Magna | 3.1 |
| 9.1.2 | 201 | Growth Inhibition study on algae | 3.2 |
| 9.2.1.1 | 301 | Persistence: Biotic degradation in air | 2.3.a |
| Annex VIII | |||
| 8.1.1 | 404 | Skin Irritation (based on in vivo) | 4.4 |
| 8.2.1 | 405 | Eye irritation (based on in vivo) | 4.9 |
| 8.4.2 | 473 | Mutagenicity - In vitro study in Mammalian Cells | 4.10 |
| 8.5.2 | 403 | Acute Inhalation Toxicity | 4.1 |
| 8.8.1 | 417 | Assessment of Toxicokinetic Behaviour: Blood-brain barrier partition / Human Serum Albumin Binding | 5.4 / 5.9 /6.4 |
| 9.1.3 | 203 | Acute Toxicity Test - Fish | 3.3 |
| 9.1.4 | 209 | Toxicity to Activated Sludge | 3.6 |
| 9.2.2 | Persistence - Abiotic degradation in air | 2.2.b | |
| 223 | Acute Toxicity to Birds | 3.12.a | |
| 9.3.1 | 121 | Adsorption/Desorption Screening | 2.6 |
| Annex IX | |||
| 8.6.2 | 408 | Sub-chronic Toxicity study (90 day) repeated dose toxicity oral | 4.14 |
| 8.7.2 | 414 | Prenatal developmental toxicity study | 4.14 |
| 9.1.5 | 211 | Daphnia magna reproduction test | 3.4 |
| 9.1.6.1 | 210 | Fish Early-Life Stage toxicity test | 3.5 |
| 9.2.1.2 | 309 | Persistence: biotic degradation in water | 2.3a |
| 9.2.1.3 | 307 | Persistence: biotic degradation in soil | 2.3a |
| 9.2.1.4 | 308 | Persistence: biotic degradation in sediment | 2.3a |
| 9.3.2 | 305 | Bioaccumulation in Aquatic Species (BAF and BCF) | 2.4a |
| 9.4.1 | 214 | Short-term Toxicity to Invertebrates (Honey Bee) | |
| Annex X | |||
| 8.6.3 | 452 | Chronic Toxicity LOAEL | 4.14 |
| 8.9.1 | 451 | Carcinogenicity | 4.12 |